Nephrin (Y1210) antibody [APR30603G]
Product Specifications
Background
Tissue Location: Specifically expressed in podocytes of kidney glomeruli
Synonyms
Nephrin, Renal glomerulus-specific cell adhesion receptor, NPHS1, NPHN
Gene Name
NPHS1
Gene ID
4868
UniProt
O60500
Chromosomal Location
Cell membrane; Single-pass type I membrane protein. Note=Predominantly located at podocyte slit diaphragm between podocyte foot processes. Also associated with podocyte apical plasma membrane.
Applications
WB, FC
Dilution
WB--1:2000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity) .
Molecular Weight
134742
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Nephrin (Y1210) antibody [APR30603G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4868
Uniprot URL
https://www.uniprot.org/uniprot/O60500
Available Sizes
Curated Selection
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