Nephrin (Y1210) antibody [APR30603G]

Product Specifications

Background

Tissue Location: Specifically expressed in podocytes of kidney glomeruli

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Nephrin (Y1210) antibody [APR30603G].

Synonyms

Nephrin, Renal glomerulus-specific cell adhesion receptor, NPHS1, NPHN

Gene Name

NPHS1

Gene ID

4868

UniProt

O60500

Chromosomal Location

Cell membrane; Single-pass type I membrane protein. Note=Predominantly located at podocyte slit diaphragm between podocyte foot processes. Also associated with podocyte apical plasma membrane.

Applications

WB, FC

Dilution

WB--1:2000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity) .

Molecular Weight

134742

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=4868

Uniprot URL

https://www.uniprot.org/uniprot/O60500

Available Sizes

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