C12orf48 Antibody (C-term) [APR30544G]
Product Specifications
Background
Tissue Location: Restricted to testis. Overexpressed in multiple cancer cells.
Synonyms
PCNA-interacting partner, PARI, PARP-1 binding protein, PARP1-binding protein, PARPBP, PARPBP, C12orf48, PARI
Gene Name
PARPBP
Gene ID
55010
UniProt
Q9NWS1
Chromosomal Location
Cytoplasm. Nucleus Note=Localizes to chromatin in response to S phase arrest but not in mitosis. Targeted to chromatin via its interaction with PCNA
Applications
WB, IHC-P, FC
Dilution
WB--1:1000 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. Antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. Binds single-strand DNA and poly (A) homopolymers. Positively regulate the poly (ADP-ribosyl) ation activity of PARP1; however such function may be indirect.
Molecular Weight
65054
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality C12orf48 Antibody (C-term) [APR30544G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=55010
Uniprot URL
https://www.uniprot.org/uniprot/Q9NWS1
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
