SCAR5 Antibody (C-term) [APR30540G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SCAR5 Antibody (C-term) [APR30540G].

Synonyms

Scavenger receptor class A member 5, Scavenger receptor hlg, SCARA5

Gene Name

SCARA5 {ECO:0000255|HAMAP-Rule:MF_03070}

Gene ID

286133

UniProt

Q6ZMJ2

Chromosomal Location

Cell membrane {ECO:0000255|HAMAP-Rule:MF_03070}; Single-pass type II membrane protein {ECO:0000255|HAMAP-Rule:MF_03070}

Applications

WB, IHC-P

Dilution

WB--1:500 WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Preferentially binds ferritin light chain (FTL) compared to heavy chain (FTH1) .