SCAR5 Antibody (C-term) [APR30540G]
Product Specifications
Synonyms
Scavenger receptor class A member 5, Scavenger receptor hlg, SCARA5
Gene Name
SCARA5 {ECO:0000255|HAMAP-Rule:MF_03070}
Gene ID
286133
UniProt
Q6ZMJ2
Chromosomal Location
Cell membrane {ECO:0000255|HAMAP-Rule:MF_03070}; Single-pass type II membrane protein {ECO:0000255|HAMAP-Rule:MF_03070}
Applications
WB, IHC-P
Dilution
WB--1:500 WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Preferentially binds ferritin light chain (FTL) compared to heavy chain (FTH1) .
Molecular Weight
53994
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SCAR5 Antibody (C-term) [APR30540G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=286133
Uniprot URL
https://www.uniprot.org/uniprot/Q6ZMJ2
Available Sizes
Curated Selection
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