SARS virus PUP4 Antibody (C-term) [APR30515G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SARS virus PUP4 Antibody (C-term) [APR30515G].

Synonyms

Protein 7a, Accessory protein 7a, Protein U122, Protein X4, 7a

Gene Name

Gene ID

1489674

UniProt

P59635

Chromosomal Location

Virion. Host endoplasmic reticulum membrane; Single-pass membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein Host Golgi apparatus membrane; Single-pass membrane protein

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Function

Plays a role as antagonist of host tetherin (BST2), disrupting its antiviral effect. Acts by binding to BST2 thereby interfering with its glycosylation. May suppress small interfering RNA (siRNA) . May bind to host ITGAL, thereby playing a role in attachment or modulation of leukocytes.