GDE1 Antibody [AMM22285G]

Product Specifications

Background

Tissue Location: Widely expressed..

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GDE1 Antibody [AMM22285G].

Synonyms

Glycerophosphodiester phosphodiesterase 1, 3.1.4.44, Membrane-interacting protein of RGS16, RGS16-interacting membrane protein, GDE1, MIR16

Gene Name

HGNC:29644

Gene ID

51573

UniProt

Q9NZC3

Chromosomal Location

Cell membrane {ECO:0000250|UniProtKB:Q9JL55}; Multi-pass membrane protein. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9JL55}; Multi-pass membrane protein. Note=Perinuclear vesicles and cell membrane {ECO:0000250|UniProtKB:Q9JL55}

Applications

Dilution

WB--1:2000

Function

Hydrolyzes the phosphodiester bond of glycerophosphodiesters such as glycerophosphoinositol (GroPIns) and glycerophosphoethanolamine (GroPEth), to yield a glycerol phosphate and an alcohol (By similarity) . Hydrolyzes glycerophospho-N-acylethanolamines to N- acylethanolamines in the brain and partipates to bioactive N- acylethanolamines biosynthesis such as anandamide (an endocannabinoid), N-palmitoylethanolamine (an anti-inflammatory), and N- oleoylethanolamine (an anorexic) . In addition, has a lysophospholipase D activity by hydrolyzing N-acyl-lysoplasmenylethanolamine (N-acyl- lysoPlsEt) to N-acylethanolamine. However lysophospholipase D activity is lower than glycerophosphodiester phosphodiesterase activity (By similarity) . Has little or no activity towards glycerophosphocholine (By similarity) .

Molecular Weight

37718

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.