HK2 (Hexokinase II) Antibody [AMM22224G]

Product Specifications

Background

Tissue Location: Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HK2 (Hexokinase II) Antibody [AMM22224G].

Synonyms

Hexokinase-2, 2.7.1.1, Hexokinase type II, HK II, Muscle form hexokinase, HK2

Gene Name

HGNC:4923

Gene ID

3099

UniProt

P52789

Chromosomal Location

Mitochondrion outer membrane; Peripheral membrane protein. Cytoplasm, cytosol Note=The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (PubMed:29298880) The interaction with the mitochondrial outer membrane via the mitochondrial-binding peptide (MBP) region promotes higher stability of the protein (PubMed:29298880) . Release from the mitochondrial outer membrane into the cytosol induces permeability transition pore (PTP) opening and apoptosis (PubMed:18350175) .

Applications

Dilution

WB--1:500-1:1000 IHC--1:400

Function

2318501726985301292988802929888018350175

Molecular Weight

102380

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.