DENR Antibody [AMM22191G]
Product Specifications
Background
Tissue Location: Highly expressed in heart and skeletal muscle and moderately expressed in the brain, placenta, liver and pancreas. Weakly expressed in the lung and kidney.
Synonyms
Density-regulated protein, DRP, Protein DRP1, Smooth muscle cell-associated protein 3, SMAP-3, DENR, DRP1
Gene Name
DENR
Gene ID
8562
UniProt
O43583
Applications
WB, IHC-P, FC, IF
Dilution
IF--1:25 FC--1:25 IHC-P--1:100~500 WB--1:1000-1:2000
Function
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
Molecular Weight
22092
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DENR Antibody [AMM22191G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8562
Uniprot URL
https://www.uniprot.org/uniprot/O43583
Available Sizes
Curated Selection
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