RAD51 Antibody [AMM22166G]
Product Specifications
Background
Tissue Location: Highly expressed in testis and thymus, followed by small intestine, placenta, colon, pancreas and ovary. Weakly expressed in breast
Synonyms
DNA repair protein RAD51 homolog 1, HsRAD51, hRAD51, RAD51 homolog A, RAD51, RAD51A, RECA
Gene Name
HGNC:9817
Gene ID
5888
UniProt
Q06609
Chromosomal Location
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Mitochondrion matrix Chromosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with RAD51AP1 and RPA2 to multiple nuclear foci upon induction of DNA damage (PubMed:20154705) . DNA damage induces an increase in nuclear levels (PubMed:20154705) . Together with FIGNL1, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) or camptothecin (CPT) treatment (PubMed:23754376) . Accumulated at sites of DNA damage in a SPIDR-dependent manner (PubMed:23509288) . Recruited at sites of DNA damage in a MCM9-MCM8-dependent manner (PubMed:23401855) Colocalizes with ERCC5/XPG to nuclear foci in S phase (PubMed:26833090) .
Applications
WB
Dilution
WB--1:1000
Function
285756582668130826253028
Molecular Weight
36966
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RAD51 Antibody [AMM22166G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5888
Uniprot URL
https://www.uniprot.org/uniprot/Q06609
Available Sizes
Curated Selection
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