MAP3K13 (LZK) Antibody (C-term) [AMM22159G]

Product Specifications

Background

Tissue Location: Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAP3K13 (LZK) Antibody (C-term) [AMM22159G].

Synonyms

HGNC:6852

Gene Name

HGNC:6852

Gene ID

9175

UniProt

O43283

Chromosomal Location

Cytoplasm. Membrane; Peripheral membrane protein

Applications

IF, WB

Dilution

WB--1:500

Form

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Function

Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB- containing complex that phosphorylates inhibitors of NF-kappa-B.

Molecular Weight

108296

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.