LYPD6B Antibody (Center) (Ascites) [AMM22143G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LYPD6B Antibody (Center) (Ascites) [AMM22143G].

Synonyms

Ly6/PLAUR domain-containing protein 6B, LYPD6B

Gene Name

LYPD6B

Gene ID

130576

UniProt

Q8NI32

Chromosomal Location

Cell membrane; Lipid-anchor, GPI- anchor

Applications

Dilution

WB--1:500~4000

Form

Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Function

Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-3 (3) :beta- 4 (2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha- 3 (2) :alpha-5:beta-4 (2) nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.