LYPD6B Antibody (Center) (Ascites) [AMM22143G]
Product Specifications
Synonyms
Ly6/PLAUR domain-containing protein 6B, LYPD6B
Gene Name
LYPD6B
Gene ID
130576
UniProt
Q8NI32
Chromosomal Location
Cell membrane; Lipid-anchor, GPI- anchor
Applications
WB
Dilution
WB--1:500~4000
Form
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Function
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-3 (3) :beta- 4 (2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha- 3 (2) :alpha-5:beta-4 (2) nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.
Molecular Weight
20656
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LYPD6B Antibody (Center) (Ascites) [AMM22143G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=130576
Uniprot URL
https://www.uniprot.org/uniprot/Q8NI32
Available Sizes
Curated Selection
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