GAS6 Antibody (Center) [ApR04999G]
Selected Variant
ApR04999G-01
Size: 50 µL
Product Specifications
Background
Tissue Location: Plasma. Isoform 1 and isoform 2 are widely expressed, isoform 1 being expressed at higher levels than isoform 2 in most tissues. Isoform 2 is the predominant form in spleen
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GAS6 Antibody (Center) [ApR04999G].
Synonyms
Growth arrest-specific protein 6, GAS-6, AXL receptor tyrosine kinase ligand, GAS6, AXLLG
Gene Name
HGNC:4168
Gene ID
2621
UniProt
Q14393
Chromosomal Location
Secreted.
Applications
WB
Dilution
WB--1:2000
Function
Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Molecular Weight
74925
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2621
Uniprot URL
https://www.uniprot.org/uniprot/Q14393
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