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(DANRE) dlc Antibody (C-Term) [ApR04884G]

Product Specifications

Background

Tissue Location: Strongly expressed in the early retina, where it precedes other delta proteins. Also expressed in cranial ganglia, in sensory epithelia including ear and lateral line and in scattered epidermal cells. In the mesoderm, expression is visible by 50% epiboly; it is expressed subsequently in the tail bud, in stripes in the presomitic mesoderm and in the posterior half of each somite. Also expressed in notochord, blood vessels and pronephros. In contrast to other delta proteins, it is not expressed in the majority of nascent primary neurons. In somites, it marks the posterior part of each formed somite, while deltaD (dld) marks the anterior part

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality (DANRE) dlc Antibody (C-Term) [ApR04884G].

Synonyms

Delta-like protein C, DeltaC, delC, dlc

Gene Name

Dlc

Gene ID

30120

UniProt

Q9IAT6

Chromosomal Location

Membrane; Single-pass type I membrane protein

Applications

WB

Dilution

WB--1:2000

Function

Acts as a ligand for Notch receptors and is involved in somitogenesis. Can activate Notch receptors. Required in somite segmentation to keep the oscillations of neighboring presomitic mesoderm cells synchronized.

Molecular Weight

72548

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=30120

Uniprot URL

https://www.uniprot.org/uniprot/Q9IAT6

Available Sizes

Curated Selection

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