(DANRE) dlc Antibody (C-Term) [ApR04884G]
Product Specifications
Background
Tissue Location: Strongly expressed in the early retina, where it precedes other delta proteins. Also expressed in cranial ganglia, in sensory epithelia including ear and lateral line and in scattered epidermal cells. In the mesoderm, expression is visible by 50% epiboly; it is expressed subsequently in the tail bud, in stripes in the presomitic mesoderm and in the posterior half of each somite. Also expressed in notochord, blood vessels and pronephros. In contrast to other delta proteins, it is not expressed in the majority of nascent primary neurons. In somites, it marks the posterior part of each formed somite, while deltaD (dld) marks the anterior part
Synonyms
Delta-like protein C, DeltaC, delC, dlc
Gene Name
Dlc
Gene ID
30120
UniProt
Q9IAT6
Chromosomal Location
Membrane; Single-pass type I membrane protein
Applications
WB
Dilution
WB--1:2000
Function
Acts as a ligand for Notch receptors and is involved in somitogenesis. Can activate Notch receptors. Required in somite segmentation to keep the oscillations of neighboring presomitic mesoderm cells synchronized.
Molecular Weight
72548
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality (DANRE) dlc Antibody (C-Term) [ApR04884G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=30120
Uniprot URL
https://www.uniprot.org/uniprot/Q9IAT6
Available Sizes
Curated Selection
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