What is the catalog number for ROCK2 Antibody (C-term) [ApR04825G]?

The catalog number for ROCK2 Antibody (C-term) [ApR04825G] is ApR04825G.

What sizes are available for ROCK2 Antibody (C-term) [ApR04825G]?

ROCK2 Antibody (C-term) [ApR04825G] is available in the following size(s): 50 µL, 100 µL, 200 µL, 400 µL.

How many pack sizes does ROCK2 Antibody (C-term) [ApR04825G] come in?

ROCK2 Antibody (C-term) [ApR04825G] is available in 4 different pack sizes.

Is ROCK2 Antibody (C-term) [ApR04825G] in stock?

ROCK2 Antibody (C-term) [ApR04825G] is currently made to order / not held in immediate stock. Contact us for lead time.

ROCK2 Antibody (C-term) [ApR04825G]

Product Specifications

Background

Tissue Location: Expressed in the brain (at protein level) .

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ROCK2 Antibody (C-term) [ApR04825G].

Synonyms

Rho-associated protein kinase 2, Rho kinase 2, Rho-associated, coiled-coil-containing protein kinase 2, Rho-associated, coiled-coil-containing protein kinase II, ROCK-II, p164 ROCK-2, ROCK2, KIAA0619

Gene Name

ROCK2

Gene ID

9475

UniProt

O75116

Chromosomal Location

Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Cytoplasmic, and associated with actin microfilaments and the plasma membrane.

Applications

Dilution

WB--1:2000

Function

Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1- p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. Plays an important role in generating the circadian rhythm of the aortic myofilament Ca (2+) sensitivity and vascular contractility by modulating the myosin light chain phosphorylation.

Molecular Weight

160900

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.