Mouse Erbb3 Antibody (P1076) [ApR04816G]

Product Specifications

Background

Tissue Location: In the muscle, expression localizes to the synaptic sites of muscle fibers

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Mouse Erbb3 Antibody (P1076) [ApR04816G].

Synonyms

Receptor tyrosine-protein kinase erbB-3, Glial growth factor receptor, Proto-oncogene-like protein c-ErbB-3, Erbb3

Gene Name

Erbb3

Gene ID

13867

UniProt

Q61526

Chromosomal Location

Membrane; Single-pass type I membrane protein

Applications

Dilution

WB--1:2000

Function

Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation.

Molecular Weight

147613

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.