Mouse Erbb3 Antibody (P1076) [ApR04816G]
Product Specifications
Background
Tissue Location: In the muscle, expression localizes to the synaptic sites of muscle fibers
Synonyms
Receptor tyrosine-protein kinase erbB-3, Glial growth factor receptor, Proto-oncogene-like protein c-ErbB-3, Erbb3
Gene Name
Erbb3
Gene ID
13867
UniProt
Q61526
Chromosomal Location
Membrane; Single-pass type I membrane protein
Applications
WB
Dilution
WB--1:2000
Function
Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation.
Molecular Weight
147613
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Mouse Erbb3 Antibody (P1076) [ApR04816G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=13867
Uniprot URL
https://www.uniprot.org/uniprot/Q61526
Available Sizes
Curated Selection
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