12-Ketochenodeoxycholic acid

12-Ketochenodeoxycholic acid 12 is a direct precursor of cholodeoxycholic acid (CDCA) . Cholodeoxycholic acid is used to cholesterol gallstones and has chemotherapeutic properties that dissolve gallstones[1].

Product Specifications

CAS Number

[2458-08-4]

UNSPSC

12352211

Hazard Statement

H315, H319

Target

Autophagy

Type

Reference compound

Related Pathways

Autophagy

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/12-ketochenodeoxycholic-acid.html

Purity

99.83

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@H](CCC(O)=O)[C@H]([C@]12C)CC[C@@]1([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC2=O

Molecular Formula

C24H38O5

Molecular Weight

406.56

Precautions

H315, H319

References & Citations

[1]Sawada, H. et al. Microbial production of chenodeoxycholic acid precursor, 12-ketochenodeoxycholic acid, from dehydrocholic acid. European Journal of Applied Microbiology and Biotechnology, 10 (1–2), 107–112.