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Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant

Product Specifications

Background

IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a total of 28 different sequence variants have been described. The three principal subtypes of IFNα-2 are designated α-2a, α-2b, and α-2c. IFNα-2b is being the predominant allele while IFNα-2a is less predominant and IFNα-2c only a minor allelic variant.

Overview

A DNA sequence encoding the mouse Ifna2 (NP_034633.2) (Cys24-Glu190) was expressed.

Synonyms

Ifa2 Protein, Mouse

Gene Name

Interferon, alpha 2

Expression System

Yeast

Tag

No tag

Endotoxin

Please contact us for more information.

Purity

> 95 % as determined by SDS-PAGE.

Activity

Measured in antiviral assays using L929 cells infected with vesicular stomatitisvirus (VSV) .The EDfor this effect is 0.15-0.9ng/mL.

Form

Lyophilized

Buffer

Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.

Function

Cytokine Proteins, Growth Factor proteins, Biological Target proteins

Molecular Weight

The recombinant mouse Ifna2 consists 167 amino acids and predicts a molecular mass of 19.4 kDa.

Storage Conditions

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

IFNA2

Species

Mouse

Protein ID

NP_034633.2

AA Sequence

Cys24-Glu190

Protein ID Link

https://www.ncbi.nlm.nih.gov/protein/NP_034633.2

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