Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant
Product Specifications
Background
IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a total of 28 different sequence variants have been described. The three principal subtypes of IFNα-2 are designated α-2a, α-2b, and α-2c. IFNα-2b is being the predominant allele while IFNα-2a is less predominant and IFNα-2c only a minor allelic variant.
Overview
A DNA sequence encoding the mouse Ifna2 (NP_034633.2) (Cys24-Glu190) was expressed.
Synonyms
Ifa2 Protein, Mouse
Gene Name
Interferon, alpha 2
Expression System
Yeast
Tag
No tag
Endotoxin
Please contact us for more information.
Purity
> 95 % as determined by SDS-PAGE.
Activity
Measured in antiviral assays using L929 cells infected with vesicular stomatitisvirus (VSV) .The EDfor this effect is 0.15-0.9ng/mL.
Form
Lyophilized
Buffer
Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Function
Cytokine Proteins, Growth Factor proteins, Biological Target proteins
Molecular Weight
The recombinant mouse Ifna2 consists 167 amino acids and predicts a molecular mass of 19.4 kDa.
Storage Conditions
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
IFNA2
Species
Mouse
Protein ID
NP_034633.2
AA Sequence
Cys24-Glu190
Protein ID Link
https://www.ncbi.nlm.nih.gov/protein/NP_034633.2
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