MCP110
MCP110 is an inhibitor of Ras/Raf-1 interaction. MCP110 blocks the interaction of Ras with Raf. MCP110 disrupts this interaction might can be used for the research of human tumors[1].
Product Specifications
CAS Number
521310-51-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Raf; Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mcp110.html
Purity
99.82
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(N(CC1=CC=C(OCC2=CC=CC=C2)C(OC)=C1)CCC3=NC=CC=C3)CCCCC4=CC=CC=C4
Molecular Formula
C33H36N2O3
Molecular Weight
508.65
Precautions
H302, H315, H319, H335
References & Citations
[1]Juran Kato-Stankiewicz, et al. Inhibitors of Ras/Raf-1 Interaction Identified by Two-Hybrid Screening Revert Ras-dependent Transformation Phenotypes in Human Cancer Cells. Proc Natl Acad Sci U S A. 2002 Oct 29;99 (22) :14398-403.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Raf; Ras
Available Sizes
Frequently Asked Questions
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