CGB5 Protein, Human, Recombinant (His Tag)
Product Specifications
Background
The human CGB5 gene encodes chorionic gonadotropin (hCG) beta 5, which is aberrantly expressed in trophoblastic neoplasm and in some non-trophoblastic neoplasms. Fucntional studies observed that it involved tumor initiation, growth, and metastatic outgrowth. Carriage of particular variants in the promoter of the CGB5 gene seems to protect against RM.
Synonyms
CGB Protein, Human; CGB5 Protein, Human; HCG Protein, Human; hCGB Protein, Human
Gene Name
Chorionic gonadotropin beta subunit 5
UniProt
P01233-1
Expression System
HEK293 Cells
Tag
C-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by SDS-PAGE.
Activity
At Leading Biology, the biological activity of a recombinant protein is routinely measured using a bioassay, e.g. chemotaxis or cell proliferation assay, enzyme assay, or a functional ELISA. When a recombinant protein is an enzyme, specific activity is derived from an enzymatic assay. Each enzyme is tested for potency by cleavage of a substrate. We are in the process of updating the biological activity data. If you have any questions regarding this update, please feel free to contact our technical support team.
Form
Lyophilized
Buffer
Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Molecular Weight
The recombinant human CGB5 comprises 156 amino acids and has a predicted molecular mass of 17 kDa. The apparent molecular mass of the protein is approximately 34 kDa in SDS-PAGE under reducing conditions.
Storage Conditions
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Product Datasheet
http://www.leading-biology.com/en/fastadmin/public/data/datasheet/S_Protein_datasheet/PH51980M2.pdf
Symbol
CGB5
Species
Human
Overview
A DNA sequence encoding the human CGB5 (P01233-1) (Met1-Gln165) was expressed with a C-terminal polyhistidine tag.
Uniprot URL
https://www.uniprot.org/uniprot/P01233-1
AA Sequence
Met1-Gln165
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