FCRL2 Protein, Human, Recombinant (His Tag)
Product Specifications
Background
Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 has robust predictive value for determining IGHV gene mutation status and clinical progression and thus may further improve prognostic definition in CLL (B-cell chronic lymphocytic leukemia) .
Synonyms
CD307b Protein, Human; FCRH2 Protein, Human; FCRL2 Protein, Human; IFGP4 Protein, Human; IRTA4 Protein, Human; SPAP1 Protein, Human; SPAP1A Protein, Human; SPAP1B Protein, Human; SPAP1C Protein, Human
Gene Name
Fc receptor like 2
Expression System
HEK293 Cells
Tag
C-His
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
> 90 % as determined by SDS-PAGE.
Activity
At Leading Biology, the biological activity of a recombinant protein is routinely measured using a bioassay, e.g. chemotaxis or cell proliferation assay, enzyme assay, or a functional ELISA. When a recombinant protein is an enzyme, specific activity is derived from an enzymatic assay. Each enzyme is tested for potency by cleavage of a substrate. We are in the process of updating the biological activity data. If you have any questions regarding this update, please feel free to contact our technical support team.
Form
Lyophilized
Buffer
Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Function
CD Molecule proteins, Receptor Proteins
Molecular Weight
The recombinant human FCRL2 consists 387 amino acids and predicts a molecular mass of 42.5 kDa.
Storage Conditions
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Product Datasheet
http://www.leading-biology.com/en/fastadmin/public/data/datasheet/S_Protein_datasheet/PH50771M2.pdf
Symbol
FCRL2
Species
Human
Protein ID
NP_110391.2
Overview
A DNA sequence encoding the human FCRL2 (NP_110391.2) (Met1-Asp395) was expressed with a polyhistidine tag at the C-terminus.
AA Sequence
Met1-Asp395
Protein ID Link
https://www.ncbi.nlm.nih.gov/protein/NP_110391.2
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