What is the catalog number for MIP-1 alpha/CCL3 Protein, Human, Recombinant (His Tag)?

The catalog number for MIP-1 alpha/CCL3 Protein, Human, Recombinant (His Tag) is PH50467Y2.

What sizes are available for MIP-1 alpha/CCL3 Protein, Human, Recombinant (His Tag)?

MIP-1 alpha/CCL3 Protein, Human, Recombinant (His Tag) is available in the following size(s): 50 µg, 1 mg.

How many pack sizes does MIP-1 alpha/CCL3 Protein, Human, Recombinant (His Tag) come in?

MIP-1 alpha/CCL3 Protein, Human, Recombinant (His Tag) is available in 2 different pack sizes.

Is MIP-1 alpha/CCL3 Protein, Human, Recombinant (His Tag) in stock?

MIP-1 alpha/CCL3 Protein, Human, Recombinant (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

MIP-1 alpha/CCL3 Protein, Human, Recombinant (His Tag)

Product Specifications

Background

CCL3 is a cytokine belonging to the CC chemokine family. Chemokines are a family of structurally related leukocyte chemoattractant cytokines that play a central role during immunoregulatory and inflammation processes. All chemokines contain four conserved cysteines linked by disulfide bonds, and two major subfamilies, namely CXC and CC, are defined on the basis of the first two cysteines which are separated by one amino acid or are adjacent. CCL3 is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes.

Overview

A DNA sequence encoding human CCL3 (NP_002974.1) (Ala23-Ala92) was expressed with a polyhistidine tag at the C-terminus.

Synonyms

G0S19-1 Protein, Human; LD78ALPHA Protein, Human; MIP-1-alpha Protein, Human; MIP1A Protein, Human; SCYA3 Protein, Human

Gene Name

Chemokine (C-C motif) ligand 3

Expression System

Yeast

Tag

C-His

Field of Research

Neuroinflammation

Endotoxin

Please contact us for more information.

Purity

> 95 % as determined by SDS-PAGE.

Activity

At Leading Biology, the biological activity of a recombinant protein is routinely measured using a bioassay, e.g. chemotaxis or cell proliferation assay, enzyme assay, or a functional ELISA. When a recombinant protein is an enzyme, specific activity is derived from an enzymatic assay. Each enzyme is tested for potency by cleavage of a substrate. We are in the process of updating the biological activity data. If you have any questions regarding this update, please feel free to contact our technical support team.

Form

Lyophilized

Buffer

Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.

Function

Cytokine Proteins, Growth Factor proteins, Immunotherapy proteins, Biological Target proteins, Cell Therapy proteins

Molecular Weight

The recombinant human CCL3 consists of 80 amino acids and predicts a molecular mass of 9.2 KDa. It migrates as an approximately 14 KDa band in SDS-PAGE under reducing conditions.

Storage Conditions

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.