VEGF B Protein, Human, Recombinant (hFc Tag)
Product Specifications
Background
Vascular endothelial growth factor-B (VEGF-B) is closely related to VEGF-A, an effector of blood vessel growth during development and disease and a strong candidate for angiogenic therapies. In detail, VEGFB can positively prevent the Ang II-induced rising in the size of cardiomyocyte as well as reduce Ang II-induced mRNA and protein levels of β-MHC (β-myosin heavy chain), BNP (brain natriuretic peptide), and ANP (atrial natriuretic peptide) . Moreover, VEGFB can regulate the decline of the Ang II-induced rising in Ca.
Synonyms
VEGFL Protein, Human; VRF Protein, Human
Gene Name
Vascular endothelial growth factor B
Expression System
HEK293 Cells
Tag
N-hFc
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
> 95 % as determined by SDS-PAGE.
Activity
Measured by its binding ability in a functional ELISA.Immobilized human S4-Fc3L3-VEGFB at 10 μg/ml (100 μL/well) can bind biotinylated human NRP1-Fc (Cat:PH50251M4), The ECof biotinylated human NRP1-Fc (Cat:PH50251M4) is 0.03-0.07μg/mL.
Form
Lyophilized
Buffer
Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Function
Cytokine Proteins, Growth Factor proteins, Biological Target proteins
Molecular Weight
The recombinant human VEGFB consists 446 amino acids and predicts a molecular mass of 47.8 kDa.
Storage Conditions
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Product Datasheet
http://www.leading-biology.com/en/fastadmin/public/data/datasheet/S_Protein_datasheet/PH50354M3.pdf
Symbol
VEGFB
Species
Human
Protein ID
NP_003368.1
Overview
A DNA sequence encoding the human VEGFB (NP_003368.1) (Pro22-Ala207) was expressed with the Fc region of human IgG1 at the N-terminus.
AA Sequence
Pro22-Ala207
Protein ID Link
https://www.ncbi.nlm.nih.gov/protein/NP_003368.1
Available Sizes
Curated Selection
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