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GPIHBP1 Protein, Human, Recombinant (His Tag)

Product Specifications

Background

GPIHBP1 (Glycosylphosphatidylinositol Anchored High-Density Lipoprotein Binding Protein 1) is a Protein Coding gene. The encoded protein is a member of the lymphocyte antigen 6 (Ly6) family. GPIHBP1 is an endothelial cell protein, which binds LPL in the subendothelial spaces and transports it to the capillary lumen. GPIHBP1 was positively correlated with LPL, and GPIHBP1 is a better marker for bodyweight decrease than LPL. GPIHBP1, a glycosylphosphatidylinositol (GPI) -anchored protein of capillary endothelial cells, transports lipoprotein lipase to the capillary lumen and is essential for the lipolytic processing of triglyceride-rich lipoproteins. Diseases associated with GPIHBP1 include Hyperlipoproteinemia, Type Id, and Hyperlipoproteinemia, Type I.

Overview

A DNA sequence encoding the human GPIHBP1 (AAH63857.1) (Met1-Ser160) was expressed with a polyhistidine tag at the C-terminus.

Synonyms

GPI-HBP1 Protein, Human; HYPL1D Protein, Human

Gene Name

Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1

Expression System

HEK293 Cells

Tag

C-His

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

> 90 % as determined by SDS-PAGE.

Activity

At Leading Biology, the biological activity of a recombinant protein is routinely measured using a bioassay, e.g. chemotaxis or cell proliferation assay, enzyme assay, or a functional ELISA. When a recombinant protein is an enzyme, specific activity is derived from an enzymatic assay. Each enzyme is tested for potency by cleavage of a substrate. We are in the process of updating the biological activity data. If you have any questions regarding this update, please feel free to contact our technical support team.

Form

Lyophilized

Buffer

Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.

Molecular Weight

The recombinant human GPIHBP1 consists 151 amino acids and predicts a molecular mass of 16.9 kDa.

Storage Conditions

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GPIHBP1

Species

Human

Protein ID

AAH63857.1

AA Sequence

Met1-Ser160

Protein ID Link

https://www.ncbi.nlm.nih.gov/protein/AAH63857.1

Frequently Asked Questions

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