NUCB1 Antibody - C-terminal region : Biotin (P102230_T100-Biotin)

Calnuc or NUCB1 belongs to the nucleobindin family. It is a major calcium-binding protein of the Golgi and is a good Golgi marker. It may be involved in calcium homeostasis. Calnuc also plays roles in regulation of levels of .-amyloid precursor protein (APP) and its proteolytic metabolites to further affect the patho/physiological functions of APP including Alzheimer's disease pathogenesis. Useful for immunohistochemistry and western blot.

REL; UBC; MDM2; CTPS2; RAD23B; PRKDC; METTL1; GTF2I; CBS; XPNPEP1; WARS; PTGS2; XPO1; SET; RBL1; MYC; HIVEP1; GNAS; GNAI3; GNAI1; KLC4; PTGS1; NDN; GNAI2; GNAO1; GNAZ

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Lin, P., et al., approved publication in the Journal of Neurochemistry. See //www.blackwell-synergy.com/loi/jnc for details (doi: 10.1111/j.1471-4159.2006.04336.x) .