GTF2B Antibody - N-terminal region : FITC (P100990_T100-FITC)
Selected Variant
P100990_T100-FITC
Size: 100 µL
Product Specifications
Gene Name
General transcription factor IIB
Gene Aliases
TF2B, TFIIB
Gene ID
2959
Swiss Prot
Q00403
Accession Number
NP_001505
Host
Rabbit
Reactivity
Human, Mouse, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2B
Target
GTF2B is the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
Partner Proteins
DRAP1; TNIP1; UBC; FBXO25; HNF4A; TCEA1; GTF2F2; GTF2F1; DEPDC7; SLC22A2; RELA; POLR2C; JAK3; HMGCL; SMURF1; THRA; TBP; POLR2E; SRA1; LSM4; LSM5; CIITA; NXF1; POU3F2; EP300; PSMA3; POLR2J; ESR1; UL48; NR1D2; NCOR1; TAF9; REST; tat; SAP25; MKX; CTDP1; POLR
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Zebrafish: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
35kDa
References & Citations
Tubon, T.C., et al., (2004) Mol. Cell. Biol. 24 (7), 2863-2874
Shipping Conditions
Wet Ice
Protein Length
316
NCBI Gene Symbol
GTF2B
NCBI GB Accession Number
GTF2B
Host or Source
Rabbit
Protein Name
Transcription initiation factor IIB
Nucleotide Accession Number
NM_001514
Peptide Sequence
NLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFK
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