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GTF2B Antibody - N-terminal region : HRP (P100989_P050-HRP)

Product Specifications

Gene Name

General transcription factor IIB

Gene Aliases

TF2B, TFIIB

Gene ID

2959

Swiss Prot

Q00403

Accession Number

NP_001505

Host

Rabbit

Reactivity

Human, Mouse, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2B

Target

GTF2B is the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

DRAP1; TNIP1; UBC; FBXO25; HNF4A; TCEA1; GTF2F2; GTF2F1; DEPDC7; SLC22A2; RELA; POLR2C; JAK3; HMGCL; SMURF1; THRA; TBP; POLR2E; SRA1; LSM4; LSM5; CIITA; NXF1; POU3F2; EP300; PSMA3; POLR2J; ESR1; UL48; NR1D2; NCOR1; TAF9; REST; tat; SAP25; MKX; CTDP1; POLR

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

35kDa

References & Citations

Elsby, L.M., (2006) EMBO Rep. 7 (9), 898-903

Shipping Conditions

Wet Ice

Product Datasheet

Anti-GTF2B (P100989_P050-HRP) antibody

Protein Length

316

NCBI Gene Symbol

GTF2B

NCBI GB Accession Number

GTF2B

Host or Source

Rabbit

Protein Name

Transcription initiation factor IIB

Nucleotide Accession Number

NM_001514

Peptide Sequence

ECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDSQNPLLSDGDLSTMIG

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