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NFATC3 Antibody - N-terminal region : FITC (P100975_P050-FITC)

Selected Variant

P100975_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

Gene Aliases

NFAT4, NFATX, NF-AT4c

Gene ID

4775

Swiss Prot

B5B2S0

Accession Number

NP_004546

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NFATC3

Target

NFATC3 is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. NFATC3 plays a role in the regulation of gene expression in T cells and immature thymocytes.The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Four transcript variants encoding distinct isoforms have been identified for this gene.

Partner Proteins

MAPK9; MAPK8; CDK6; NCOA3; TTF1; CSNK1A1; FOS

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

115kDa

References & Citations

Manley, K., (2006) J. Virol. 80 (24), 12079-12085

Shipping Conditions

Wet Ice

Protein Length

1068

NCBI Gene Symbol

NFATC3

NCBI GB Accession Number

NFATC3

Host or Source

Rabbit

Protein Name

Nuclear factor of activated T-cells c3 isoform IB-Xa EMBL ACG55625.1

Nucleotide Accession Number

NM_004555

Peptide Sequence

AVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSI

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