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NFATC3 Antibody - N-terminal region: FITC (P100975_P050-FITC)

Product Specifications

Gene Name

Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

Gene Aliases

NFAT4, NFATX, NF-AT4c

Gene ID

4775

Swiss Prot

B5B2S0

Accession Number

NP_004546

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NFATC3

Target

NFATC3 is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. NFATC3 plays a role in the regulation of gene expression in T cells and immature thymocytes.The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Four transcript variants encoding distinct isoforms have been identified for this gene.

Partner Proteins

MAPK9; MAPK8; CDK6; NCOA3; TTF1; CSNK1A1; FOS

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

115kDa

Shipping Conditions

Wet Ice

Protein Length

1068

NCBI Gene Symbol

NFATC3

Protein Name

Nuclear factor of activated T-cells c3 isoform IB-Xa EMBL ACG55625.1

Nucleotide Accession Number

NM_004555

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