PC4 Antibody - middle region: FITC (P100960_T100-FITC)
Product Specifications
Gene Name
SUB1 homolog (S. cerevisiae)
Gene Aliases
P15, PC4, p14
Gene ID
10923
Swiss Prot
P53999
Accession Number
NP_006704
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PC4
Target
PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.
Partner Proteins
HUWE1; SUB1; UBC; rev; CLK4; CDK2; HNF4A; FN1; CSNK2A1; SMURF1; RPL18A; LAMP2; CDC5L; APP; YWHAZ; GTF3C1; ELAVL1; SUMO2; HDGF; Shoc2; Kif1c; POLR2B; POLR2A; CBX5; RCOR1; REST; BANF1; ADAP1; GTF2A1L; EP300; POU2AF1; CSTF2; TBP; TAF1; PCNA; HSF1; PSIP1; SP1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Sample Type
There is BioGPS gene expression data showing that SUB1 is expressed in HepG2
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
14kDa
Shipping Conditions
Wet Ice
Protein Length
127
NCBI Gene Symbol
SUB1
Protein Name
Activated RNA polymerase II transcriptional coactivator p15
Nucleotide Accession Number
NM_006713
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