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MAX Antibody - N-terminal region : FITC (P100953_P050-FITC)

Product Specifications

Gene Name

MYC associated factor X

Gene Aliases

BHLHd4

Gene ID

4149

Swiss Prot

P61244

Accession Number

NP_660087

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the n terminal region of human MAX

Target

MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation.The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full length nature for some of them is unknown. The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown.

Partner Proteins

USP37; UNC45A; BANP; FBXW11; MXI1; RPL35; TUBA1A; RPL34; GABBR1; FUS; FTH1; MYC; MXD1; MGA; PLIN3; HSP90AA1; TCF3; MYCN; CPSF6; ARL6IP5; KMT2D; HNRNPH2; DYNC1H1; CSTF2; SNIP1; PPP1CC; PPP1CB; PPP1CA; USF1; PCGF6; EP400; DMAP1; WDR5; BRD8; KAT5; MNT; MAX

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Sample Type

There is BioGPS gene expression data showing that MAX is expressed in COLO205

Concentration

0.5 mg/ml

Homology

Dog: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

17kDa

References & Citations

Faiola, F., (2007) Biochem. J. 403 (3), 397-407

Shipping Conditions

Wet Ice

Protein Length

151

NCBI Gene Symbol

MAX

NCBI GB Accession Number

MAX

Host or Source

Rabbit

Protein Name

Protein max

Nucleotide Accession Number

NM_145112

Peptide Sequence

MSDNDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKAS

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