LMO2 Antibody - N-terminal region : Biotin (P100952_P050-Biotin)
Selected Variant
P100952_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
LIM domain only 2 (rhombotin-like 1)
Gene Aliases
TTG2, LMO-2, RBTN2, RHOM2, RBTNL1
Gene ID
4005
Swiss Prot
P25791
Accession Number
NP_005565
Host
Rabbit
Reactivity
Mouse, Rat, Dog, Guinea Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human LMO2
Target
LMO2 acts with TAL1/SCL to regulate red blood cell development. LMO2 also acts with LDB1 to maintain erythroid precursors in an immature state.LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
ADAMTSL4; MBIP; HOOK1; TFPT; NOTCH2NL; KRTAP10-7; CCDC36; NUTM1; SPERT; FAM154A; CLHC1; KRT40; SSX2IP; CMTM5; MRFAP1L1; IFT43; C1orf94; LZTS2; TSC22D4; DBF4B; CCDC33; RINT1; NIF3L1; TRIM54; AGTRAP; ZFP64; BANP; STAT3; STAT1; SOX5; SKP1; ROCK1; REL; PRKG1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Dog: 100%; Guinea Pig: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
18kDa
References & Citations
Yuan, W., (2008) Leukemia 22 (5), 1067-1071
Shipping Conditions
Wet Ice
Protein Length
158
NCBI Gene Symbol
LMO2
NCBI GB Accession Number
LMO2
Host or Source
Rabbit
Protein Name
Rhombotin-2
Nucleotide Accession Number
NM_005574
Peptide Sequence
GGGARAPEGVRAPAAGQPRATKGAPPPPGTPPPSPMSSAIERKSLDPSEE
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