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GTF2H1 Antibody - middle region : Biotin (P100929_P050-Biotin)

Product Specifications

Gene Name

General transcription factor IIH, polypeptide 1, 62kDa

Gene Aliases

P62, BTF2, TFB1, TFIIH

Gene ID

2965

Swiss Prot

P32780

Accession Number

NP_005307

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human GTF2H1

Target

GTF2H1 is the component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.

Partner Proteins

UBC; CDK7; TP53; RNF11; ERCC5; KLF1; HNF4A; E2F1; TCEA1; POLR2A; GTF2E1; POLR2C; KPNA3; GTF2H2; ACTN1; USHBP1; UVSSA; TRIOBP; TNIP1; REEP5; MMS19; ERCC2; GTF2H4; GTF2H3; ERCC3; RB1; MNAT1; tat; GTF2F1; CTD; RAD23A; XPC; XPA; RPA2; RPA1; RAD23B; ERCC4; ERC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

GTF2H1 is supported by BioGPS gene expression data to be expressed in ACHN

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

62kDa

References & Citations

Bethke, L., (2008) J. Natl. Cancer Inst. 100 (4), 270-276

Shipping Conditions

Wet Ice

Protein Length

548

NCBI Gene Symbol

GTF2H1

NCBI GB Accession Number

GTF2H1

Host or Source

Rabbit

Protein Name

General transcription factor IIH subunit 1

Nucleotide Accession Number

NM_005316

Peptide Sequence

ERFQVTKLCPFQEKIRRQYLSTNLVSHIEEMLQTAYNKLHTWQSRRLMKK

Subunit

1

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