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NHLH1 Antibody - N-terminal region : Biotin (P100926_P050-Biotin)

Selected Variant

P100926_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Nescient helix loop helix 1

Gene Aliases

HEN1, NSCL, NSCL1, bHLHa35

Gene ID

4807

Swiss Prot

Q02575

Accession Number

NP_005589

Host

Rabbit

Reactivity

Human, Cow

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NHLH1

Target

The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC, LYL1, E2A, and SCLThe helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040) .[supplied by OMIM]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments.

Partner Proteins

CENPP; PIM1; INO80E; PSME2; HIVEP1; ELAVL1; LMO4; CSRP3; LMO1; LMO2; xlmo1; TCF3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 92%; Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

14kDa

References & Citations

Manetopoulos, C., (2003) Biochem. Biophys. Res. Commun. 307 (4), 891-899

Shipping Conditions

Wet Ice

Protein Length

133

NCBI Gene Symbol

NHLH1

NCBI GB Accession Number

NHLH1

Host or Source

Rabbit

Protein Name

Helix-loop-helix protein 1

Nucleotide Accession Number

NM_005598

Peptide Sequence

GGPGGGQARGPEPGEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIR

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