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EN1 Antibody - C-terminal region : FITC (P100923_P050-FITC)

Selected Variant

P100923_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Engrailed homeobox 1

Gene Aliases

ENDOVESLB

Gene ID

2019

Swiss Prot

Q05925

Accession Number

NP_001417

Host

Rabbit

Reactivity

Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human EN1

Target

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

TLE1; PAX6; JUN

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Guinea Pig: 93%; Rabbit: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

40kDa

References & Citations

Atit, R., (2006) Dev. Biol. 296 (1), 164-176

Shipping Conditions

Wet Ice

Protein Length

392

NCBI Gene Symbol

EN1

NCBI GB Accession Number

EN1

Host or Source

Rabbit

Protein Name

Homeobox protein engrailed-1

Nucleotide Accession Number

NM_001426

Peptide Sequence

LMGSANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSGPRTRKLKKKKNEK

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