EN1 Antibody - C-terminal region : FITC (P100923_P050-FITC)
Selected Variant
P100923_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Engrailed homeobox 1
Gene Aliases
ENDOVESLB
Gene ID
2019
Swiss Prot
Q05925
Accession Number
NP_001417
Host
Rabbit
Reactivity
Guinea Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human EN1
Target
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
TLE1; PAX6; JUN
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Guinea Pig: 93%; Rabbit: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
40kDa
References & Citations
Atit, R., (2006) Dev. Biol. 296 (1), 164-176
Shipping Conditions
Wet Ice
Protein Length
392
NCBI Gene Symbol
EN1
NCBI GB Accession Number
EN1
Host or Source
Rabbit
Protein Name
Homeobox protein engrailed-1
Nucleotide Accession Number
NM_001426
Peptide Sequence
LMGSANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSGPRTRKLKKKKNEK
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