CEBPA Antibody - N-terminal region : FITC (P100908_P050-FITC)
Product Specifications
Gene Name
CCAAT/enhancer binding protein (C/EBP), alpha
Gene Aliases
CEBP, C/EBP-alpha
Gene ID
1050
Swiss Prot
P49715
Accession Number
NP_004355
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Guinea Pig, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPA
Target
CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. It has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Partner Proteins
CEBPB; ZBTB16; RARA; HDAC1; BHLHE41; UBC; CEBPE; BATF2; BATF3; YY1AP1; ATF5; BATF; FOSL1; FOS; DBP; CEBPG; CEBPA; ATF4; ATF3; UBE3A; SKP2; RASGRF1; C1QBP; CDKN1A; SRA1; CDK4; PIAS1; Fbxw7; GRIN3A; RAB34; NAA16; POLR1E; MRTO4; AK5; MACF1; KAT5; AKAP9; SMC1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Sample Type
CEBPA is supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/ml
Homology
Cow: 100%; Guinea Pig: 90%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
38kDa
References & Citations
Zhu, Q.S., et al., (2004) J. Biol. Chem. 279 (29), 29902-29910
Shipping Conditions
Wet Ice
Protein Length
358
NCBI Gene Symbol
CEBPA
NCBI GB Accession Number
CEBPA
Host or Source
Rabbit
Protein Name
CCAAT/enhancer-binding protein alpha
Nucleotide Accession Number
NM_004364
Peptide Sequence
GGICEHETSIDISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGG
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