NFKBIL2 Antibody - middle region: Biotin (P100874_P050-Biotin)
Product Specifications
Gene Name
Tonsoku-like, DNA repair protein
Gene Aliases
IKBR, SEMDSP, NFKBIL2
Gene ID
4796
Swiss Prot
Q96HA7
Accession Number
NP_038460
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human NFKBIL2
Target
NFKBIL2 is thought to be a negative regulator of NF-kappa-B mediated transcription. It may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
Partner Proteins
HIST3H3; MCM6; MCM2; MMS22L; ASF1B; ASF1A; UBC; MYC; MAU2; SLC25A5; SUPT16H; SUGT1; AIFM1; HIST1H2BL; XRCC5; SSRP1; SLC25A3; TONSL; MCM4; HIST1H2AE; HIST1H1B; HIST1H1C; XRCC6; GSK3B; MCM7; MCM5; MCM3; EWSR1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/mL
Homology
Dog: 84%; Human: 100%; Mouse: 83%; Rat: 83%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
133kDa
Shipping Conditions
Wet Ice
Protein Length
1219
NCBI Gene Symbol
TONSL
Protein Name
Tonsoku-like protein
Nucleotide Accession Number
NM_013432
Curated Selection
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