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TCF3 Antibody - C-terminal region : HRP (P100871_T100-HRP)

Selected Variant

P100871_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

Transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)

Gene Aliases

E2A, E47, p75, AGM8, ITF1, VDIR, TCF-3, bHLHb21

Gene ID

6929

Swiss Prot

P15923

Accession Number

AAA56830

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human TCF3

Target

TCF3 contains 1 basic helix-loop-helix (bHLH) domain. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. TCF3 binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.

Partner Proteins

ID3; FAM115A; TLE1; RNF14; UBC; SCX; MAPKAPK2; MAPKAPK3; TCF21; Ube2i; ID2; FUS; CTNNB1; RPL37; MAX; USF1; TCF12; TCF3; MYOD1; Rufy1; Tfap4; Rpa1; Tbx6; Ncl; Twist2; SUPT3H; TRRAP; KAT2A; TADA2A; FOXH1; ELAVL1; TCF24; SETSIP; FLG2; BHLHA15; MYL6B; TIMM50

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Sample Type

TCF3 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Pig: 92%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

48kDa

Shipping Conditions

Wet Ice

Protein Length

440

NCBI Gene Symbol

TCF3

NCBI GB Accession Number

TCF3

Host or Source

Rabbit

Protein Name

Transcription factor E2-alpha

Nucleotide Accession Number

NM_001136139

Peptide Sequence

EENTSAADHSEEEKKELKAPRARTSPDEDEDDLLPPEQKAEREKERRVAN

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