SRF Antibody - N-terminal region: FITC (P100866_T100-FITC)
Product Specifications
Gene Name
Serum response factor (c-fos serum response element-binding transcription factor)
Gene Aliases
MCM1
Gene ID
6722
Swiss Prot
P11831
Accession Number
NP_003122
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SRF
Target
SRF is a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs) .
Partner Proteins
Camk2d; ZIC3; ELK1; SRFBP1; SRF; NFKB1; PRKDC; CIRBP; ALDH3A1; SUMO1; UBE2I; SHBG; TRIM63; KDM6A; MYOCD; MKL1; CNTN2; CSNK2A1; SMARCA4; PELP1; KAT5; HDAC4; EPC1; SMAD7; HDAC3; MKL2; ATF6; BARX2; MAPKAPK2; FHL3; GATA4; CAMK2A; HOPX; PYCARD; NKX2-3; MINPP1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
CHIP, WB
Sample Type
SRF is supported by BioGPS gene expression data to be expressed in Jurkat
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
52kDa
Shipping Conditions
Wet Ice
Protein Length
508
NCBI Gene Symbol
SRF
Protein Name
Serum response factor
Nucleotide Accession Number
NM_003131
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