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GTF2E1 Antibody - N-terminal region : HRP (P100863_P050-HRP)

Product Specifications

Gene Name

General transcription factor IIE, polypeptide 1, alpha 56kDa

Gene Aliases

FE, TF2E1, TFIIE-A

Gene ID

2960

Swiss Prot

P29083

Accession Number

NP_005504

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2E1

Target

GTF2E1 belongs to the TFIIE alpha subunit family. It recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

Partner Proteins

UBC; AARSD1; ACBD3; XPO5; SH3GLB2; OXR1; NSUN2; RPUSD2; SNF8; EFTUD2; TTC1; SH3GL1; SARS; HARS; SRPK2; TCEA1; GTF2H1; GTF2E2; CDK7; APP; tat; GTF2F1; ELAVL1; ZSCAN1; ZBTB9; TRIM15; PCBD2; TRIM29; CBFA2T2; IKBKG; ATF7IP; TAF6; GTF2B; TRIM24; SND1; GTF2H4

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Sample Type

GTF2E1 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 92%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

49kDa

References & Citations

Okuda, M., (2008) EMBO J. 27 (7), 1161-1171

Shipping Conditions

Wet Ice

Protein Length

439

NCBI Gene Symbol

GTF2E1

NCBI GB Accession Number

GTF2E1

Host or Source

Rabbit

Protein Name

General transcription factor IIE subunit 1

Nucleotide Accession Number

NM_005513

Peptide Sequence

DHMRRRIETDERDSTNRASFKCPVCSSTFTDLEANQLFDPMTGTFRCTFC

Subunit

1

Frequently Asked Questions

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