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PAX2 Antibody - middle region : FITC (P100859_T100-FITC)

Selected Variant

P100859_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

Paired box 2

Gene Aliases

FSGS7, PAPRS

Gene ID

5076

Swiss Prot

Q02962

Accession Number

NP_003979

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PAX2

Target

PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia.

Partner Proteins

BBS7; BBS4; BBS2; BBS1; RB1; BRCA1; SFRP2; PAXIP1; WT1; MAPK8IP1; MAPK8; ID2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 92%; Sheep: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Muratovska, A., et al., (2003) Oncogene 22 (39), 7989-7997.

Shipping Conditions

Wet Ice

Protein Length

417

NCBI Gene Symbol

PAX2

NCBI GB Accession Number

PAX2

Host or Source

Rabbit

Protein Name

Paired box protein Pax-2

Nucleotide Accession Number

NM_003988

Peptide Sequence

VSSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDS

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