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ELK3 Antibody - middle region : FITC (P100855_P050-FITC)

Selected Variant

P100855_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

ELK3, ETS-domain protein (SRF accessory protein 2)

Gene Aliases

ERP, NET, SAP2, SAP-2

Gene ID

2004

Swiss Prot

P41970

Accession Number

NP_005221

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ELK3

Target

ELK3 is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. ELK3 is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present.The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-619 Z36715.1 1-619 620-2180 BC017371.1 549-2109

Partner Proteins

APP; TOP1; UBC; PIAS1; MAPK9; CTBP1; MAPK8; ID2; MAPK14; TCF3

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 84%; Guinea Pig: 78%; Horse: 78%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

References & Citations

Wasylyk, C., (2008) Cancer Res. 68 (5), 1275-1283

Shipping Conditions

Wet Ice

Protein Length

407

NCBI Gene Symbol

ELK3

NCBI GB Accession Number

ELK3

Host or Source

Rabbit

Protein Name

ETS domain-containing protein Elk-3

Nucleotide Accession Number

NM_005230

Peptide Sequence

RTVIRFVTNKTDKHVTRPVVSLPSTSEAAAASAFLASSVSAKISSLMLPN

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