MEF2C Antibody - middle region : FITC (P100852_P050-FITC)
Product Specifications
Gene Name
Myocyte enhancer factor 2C
Gene Aliases
DEL5q14.3, C5DELq14.3
Gene ID
4208
Swiss Prot
Q06413
Accession Number
NP_002388
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human MEF2C
Target
MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. MEF2C may also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Partner Proteins
PLA2G12A; UBC; ASCL1; SUMO1; HDAC7; HDAC5; HDAC4; MYOD1; IFRD1; NCOA2; SIRT1; HDAC9; COPS5; YWHAZ; SPTBN1; MAPK7; EPAS1; MAPK14; VGLL2; VGLL4; TWIST2; GATA4; SOX18; EP300; SMAD2; MEF2D; MEF2C; NOTCH1; TEAD1; SP1; CCNB1; CDK1; CSNK2A1; MYOG
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
51kDa
References & Citations
Nagel, S., (2008) Leukemia 22 (3), 600-607
Shipping Conditions
Wet Ice
Protein Length
473
NCBI Gene Symbol
MEF2C
NCBI GB Accession Number
MEF2C
Host or Source
Rabbit
Protein Name
Myocyte-specific enhancer factor 2C
Nucleotide Accession Number
NM_002397
Peptide Sequence
PPSALSQLGACTSTHLSQSSNLSLPSTQSLNIKSEPVSPPRDRTTTPSRY
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