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GABPA Antibody - C-terminal region : Biotin (P100832_T100-Biotin)

Product Specifications

Gene Name

GA binding protein transcription factor, alpha subunit 60kDa

Gene Aliases

NFT2, NRF2, NRF2A, E4TF1A, E4TF1-60, RCH04A07

Gene ID

2551

Swiss Prot

Q06546

Accession Number

NP_002031

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human GABPA

Target

GA Binding Protein . chain (GABP-. subunit, GABPA, nuclear respiratory factor-2 subunit . transcription factor E4TF1-60) is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype.

Partner Proteins

UBC; NCOA7; KCTD12; TSEN34; DIABLO; CUTC; RAB3GAP2; LIMCH1; RAB3GAP1; GNE; KPNA1; YY1; GABPB1; PINX1; APP; KEAP1; SUMO2; HDAC1; EP300; SP3; CREBBP; HCFC1; SP1; ATF1; MED1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

GABPA is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

51kDa

References & Citations

Xue, H.H., et al., (2004) Nat.Immunol.5 (10),1036-1044

Shipping Conditions

Wet Ice

Protein Length

454

NCBI Gene Symbol

GABPA

NCBI GB Accession Number

GABPA

Host or Source

Rabbit

Protein Name

GA-binding protein alpha chain

Nucleotide Accession Number

NM_002040

Peptide Sequence

KWGQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIG

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