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TAF1A Antibody - C-terminal region : HRP (P100802_P050-HRP)

Product Specifications

Gene Name

TATA box binding protein (TBP) -associated factor, RNA polymerase I, A, 48kDa

Gene Aliases

SL1, RAFI48, TAFI48, MGC:17061

Gene ID

9015

Swiss Prot

Q9NWA1

Accession Number

NP_647603

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human TAF1A

Target

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1A encodes the smallest SL1-specific TAF.

Partner Proteins

C11orf57; JMJD6; TBP; Taf1c; Taf1b; BKRF1; UBC; TAF12; TAF1D; HIST1H4A; HIST1H3A; HIST2H2BE; HIST2H2AC; ESR1; SET; TAF1A; RUNX2; TP53; CD3EAP; HIST4H4; HIST3H3; ANP32A; UBTF; RRN3; MYC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 78%; Dog: 85%; Horse: 85%; Human: 100%; Mouse: 85%; Pig: 85%; Rabbit: 85%; Rat: 85%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

40kDa

References & Citations

Di et al., (2000) Cytogenet. Cell Genet. 89 (1-2), 133-136

Shipping Conditions

Wet Ice

Protein Length

336

NCBI Gene Symbol

TAF1A

NCBI GB Accession Number

TAF1A

Host or Source

Rabbit

Protein Name

TATA box-binding protein-associated factor RNA polymerase I subunit A

Nucleotide Accession Number

NM_139352

Peptide Sequence

CEKAFVAGLLLGKGCRYFRYILKQDHQILGKKIKRMKRSVKKYSIVNPRL

Subunit

A

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