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RXRB Antibody - N-terminal region : Biotin (P100796_P050-Biotin)

Product Specifications

Gene Name

Retinoid X receptor, beta

Gene Aliases

NR2B2, DAUDI6, RCoR-1, H-2RIIBP

Gene ID

6257

Swiss Prot

P28702

Accession Number

NP_068811

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RXRB

Target

RXRB is a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA) . This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA) . This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA) . This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

NR1H3; RARB; UBC; PTMS; CACNA1B; SPOP; RARA; ZDHHC12; VDR; GRIP1; SRA1; MED1; Cebpb; SUMO2; NR1I2; NR1H2; NR2C2; THRB; SRC; RARG; PPARG; PPARD; NR4A2; MAP4; GTF2H1; NR3C1; TAF11; THRA; TACC2; AKAP13; NR0B2; NR2E3; NCOA1; NRIP1; NCOA3; RXRB

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

RXRB is strongly supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

57kDa

References & Citations

Chang, S.C., (er) Carcinogenesis (2008) In press

Shipping Conditions

Wet Ice

Protein Length

533

NCBI Gene Symbol

RXRB

NCBI GB Accession Number

RXRB

Host or Source

Rabbit

Protein Name

Retinoic acid receptor RXR-beta

Nucleotide Accession Number

NM_021976

Peptide Sequence

GDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPPPPP

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