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RELA Antibody - N-terminal region : HRP (P100779_T100-HRP)

Selected Variant

P100779_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

V-rel reticuloendotheliosis viral oncogene homolog A (avian)

Gene Aliases

P65, CMCU, NFKB3

Gene ID

5970

Swiss Prot

Q04206

Accession Number

NP_068810

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RELA

Target

P65 is a subunit of the nuclear factor kappa-B, a second messenger, which activates the transcription of a number of genes in multiple tissues. The inhibitory effect of I-kappa-B upon NF-kappa-B in the cytoplasm is exerted primarily through the interaction with p65. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappa-B complex.

Partner Proteins

GAN; CCND1; ABCA1; UBC; TCF4; SRSF7; RELA; REL; PRKDC; PLG; PEX1; NFKB2; NFKB1; MUC3A; KRT5; REV1; TXN2; FBXW11; IL1RN; IKBKB; HSPA5; HDAC1; EP300; CREBBP; MAP3K8; CHEK1; CDKN2A; CDK4; SPATA31A3; POTEJ; POTEE; PIWIL4; DIS3L2; DCD; IKBKG; CHUK; PLA2G4A; ST

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

60kDa

References & Citations

Ruben, S.M., et al., (1991) Science 251 (5000) 1490-1493.

Shipping Conditions

Wet Ice

Protein Length

551

NCBI Gene Symbol

RELA

NCBI GB Accession Number

RELA

Host or Source

Rabbit

Protein Name

Transcription factor p65

Nucleotide Accession Number

NM_021975

Peptide Sequence

VEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPG

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