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MYBL2 Antibody - N-terminal region : HRP (P100748_P050-HRP)

Product Specifications

Gene Name

V-myb myeloblastosis viral oncogene homolog (avian) -like 2

Gene Aliases

BMYB, B-MYB

Gene ID

4605

Swiss Prot

P10244

Accession Number

NP_002457

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MYBL2

Target

Myb-Related Protein B (MYBL2), a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.

Partner Proteins

CCNA1; CDK2; CCNE1; LIN54; SPTBN1; SPTA1; FLNA; CLTC; CLTA; LIN9; UBE2D4; CXCR4; LIN52; LIN37; RBL1; RBBP4; SUMO2; MAP1LC3B; MAPK6; NLK; HIPK2; CREBBP; ZBTB9; TRIM15; LZTR1; CDK9; ZNF622; UBB; TTF2; EP300; SND1; SKP2; MYBL2; NCOR1; NCOR2; PARP1; CCND1; CC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

MYBL2 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 85%; Horse: 100%; Human: 100%; Rabbit: 92%; Rat: 78%; Zebrafish: 83%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

79kDa

References & Citations

Tashiro, S., et al., (2004) J.Biol.Chem.279 (17),17715-17722

Shipping Conditions

Wet Ice

Protein Length

700

NCBI Gene Symbol

MYBL2

NCBI GB Accession Number

MYBL2

Host or Source

Rabbit

Protein Name

Myb-related protein B

Nucleotide Accession Number

NM_002466

Peptide Sequence

RCEDLDELHYQDTDSDVPEQRDSKCKVKWTHEEDEQLRALVRQFGQQDWK

Frequently Asked Questions

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